alexisWhat does Alexis mean? A lexis as a boys' name (also used more widely as girls' name Alexis) is pronounced a-LEX-iss. It is of Greek orin, and the meaning of Alexis is defender. OftenAlexis · Videos · Haute couture · Prêt à porter · Bridal · News · Contacts · en English (Anglais) · Alexis · Videos · Haute couture · Prêt à porter · Bridal